New results about microtubules as quantum systems
Keywords:
microtubules, coherence, quantum consciousness' topological geometrodynamicsAbstract
The latest news in quantum biology is the observation by the group led by Anirban Bandy-opadhyay about detection of quantum vibration in microtubule scale - their lengths vary up to50 m. If this observation can be replicated, one can speak about breakthrough in quantumconsciousness.The ndings reported in an earlier talk of Banduopadhyay give support for the general TGDinspired view about topological quantum computation (TQC) and allow for a rather detailedmodel in the case of microtubules. The idea is that ux tubes form a 2-D coordinate grid consistingof parallel ux tubes in two dierent directions. Crossing points would be associated with tubulinsand the conformational state of tubulin could dene a bit coding whether the braid strandsdening coordinate lines are braided or not (swap or not). In this manner any bit pattern atmicrotubule denes a particular TQC program. If also conformations are quantum superposed,one would have "quantum-quantum computation". It however seems that conformation changeis irreversible chemical reaction so that this option is not feasible.The TGD inspired modication of the proposal in terms of ux tube coordinate grids makingpossible TQC architectures with tubulin dimers dening bits dening in turn TQC program looksrather natural. Coordinate grids can be xed on basis of the experimental ndings and thereare 8 of them. The interpretation is in terms of dierent resolutions. The grids for A and Btype lattices are related by 2 twist for the second end of the basic 13-unit for microtubule. Anattractive interpretation for the resonance frequencies is in terms of phase transitions between Aand B type lattices. If A type lattices can be generated only in phase transitions induced by ACstimulus at resonance frequencies, one could understand their experimental absence, which is astrong objection against Penrose-Hamero model.TGD suggests also a generalization of the very notion of TQC to 2-braid TQC with 2-D stringworld sheets becoming knotted in 4-D space-time. Now qubits (or their generalizations) couldcorrespond to states of ux tubes dening braid strands as Penrose and Hamero seem to suggestand the emergence of MTs could be seen as an evolutionary leap due to the emergence of a newabstraction level in cognitive processing.References
[J1] Discovery-of-quantum-vibrations-in-microtubules-inside-brain-neurons-corroboratescontroversial-
-year-old-theory-of-consciousness? http://www.kurzweilai.net/
discovery-of-quantum-vibrations-in-microtubules-inside-brain-neurons-corroborates-controve[J2] Acousto-conformational transitions in cytoskeletal microtubules: implications for intracellular
information processing. Nanobiology, 1:457{468, 1992.
[J3] A. Bandyopadhyay. Experimental Studies on a Single Microtubule (Google Workshop on Quantum
Biology), 2011.
[J4] C. F. Blackman. Eect of Electrical and Magnetic Fields on the Nervous System, pages 331{355.
Plenum, New York, 1994.
[J5] E.-M. Mandelkow et al. On the Surface Lattice of Microtubules : Helix Starts, Protolament
Number, Seam, and Handedness. http: // www. ncbi. nlm. nih. gov/ pmc/ articles/
PMC2114131/ pdf/ jc10231067. pdf , 1985.
[J6] J. R. Reimers et al. PenroseHamero orchestrated objective-reduction proposal for human consciousness
is not biologically feasible. Phys Rev E, 80:021912021916, 2009.
[J7] J. R. Reimers et al. Weak, strong, and coherent regimes of Frhlich condensation and their
applications to terahertz medicine and quantum consciousness. Proc Natl Acad Sci, 106:4219{
, 2009.
[J8] M. Kikkawa et al. Direct visualization of the microtubule lattice seam both in vitro and in vivo.
JCB. http: // jcb. rupress. org/ content/ 127/ 6/ 1965. abstract , 127(6), 1994.
[J9] N. Usui et al. Very high frequency oscillations (over 1000 Hz) in human epilepsy. Clin Neuro-
physiol, 121:1825{1831, 2010.
[J10] S. Hamero et al. Conduction pathways in microtubules, biological quantum computation, and
consciousness. Biosystems. http: // www. quantumconsciousness. org/ biosystemselsevier.
htm , 64(1-3):149{168, 2002.
[J11] S. Sahu et al. Atomic water channel controlling remarkable properties of a single brain microtubule:
correlating single protein to its supramolecular assembly. Biosens Bioelectron, pages
{148, 2013.
[J12] S. Sahu et al. Multi-level memory-switching properties of a single brain microtubule . Appl Phys
Lett. http: // dx. doi. org/ 10. 1063/ 1. 4793995 , 102(123701), 2013.
[J13] H. Froehlich. Bose condensation of strongly excited longitudinal electric modes. Phys Lett A,
:402{403, 1968.
[J14] A. Bandyopadhyay G. Ghosh, S. Sahu. Evidence of massive global synchronization and the
consciousness: Comment on "Consciousness in the universe: A review of the 'Orch OR' theory"
by Hamero and Penrose. Biosens Bioelectron, 2013.
[J15] S. Gupta and S. Hamero. The Possibility of MAPs as Quantum Logic Gates in Neuronal Microtubules.
https: // sbs. arizona. edu/ project/ consciousness/ report_ poster_ detail.
php? abs= 1435 , 2013.
[J16] S. Hamero and R. Penrose. Reply to criticism of the Orch OR qubitOrchestrated objective
reduction is scientically justied. ScienceDirect. http: // www. sciencedirect. com , 2013.
[J17] S. R. Hamero and R. Penrose. Orchestrated reduction of quantum coherence in brain micro-
tubules: A model for consciousness. MIT Press, Cambridge, 1996.
[K1] M. Pitkanen. Dark Matter Hierarchy and Hierarchy of EEGs. In TGD and EEG. Onlinebook.
http://tgdtheory.fi/public_html/tgdeeg/tgdeeg.html#eegdark, 2006.
[K2] M. Pitkanen. DNA as Topological Quantum Computer. In Genes and Memes. Onlinebook.
http://tgdtheory.fi/public_html/genememe/genememe.html#dnatqc, 2006.
[K3] M. Pitkanen. Genes and Memes. In Genes and Memes. Onlinebook. http://tgdtheory.fi/
public_html/genememe/genememe.html#genememec, 2006.
[K4] M. Pitkanen. Homeopathy in Many-Sheeted Space-Time. In Bio-Systems as Conscious Holo-
grams. Onlinebook. http://tgdtheory.fi/public_html/hologram/hologram.html#homeoc,
[K5] M. Pitkanen. Knots and TGD. In Quantum Physics as Innite-Dimensional Geometry. Onlinebook.
http://tgdtheory.fi/public_html/tgdgeom/tgdgeom.html#knotstgd, 2006.
[K6] M. Pitkanen. Negentropy Maximization Principle. In TGD Inspired Theory of Consciousness.
Onlinebook. http://tgdtheory.fi/public_html/tgdconsc/tgdconsc.html#nmpc, 2006.
[K7] M. Pitkanen. Nuclear String Hypothesis. In Hyper-nite Factors and Dark Mat-
ter Hierarchy. Onlinebook. http://tgdtheory.fi/public_html/neuplanck/neuplanck.html#
nuclstring, 2006.
[K8] M. Pitkanen. Quantum Antenna Hypothesis. In Quantum Hardware of Living Matter. Onlinebook.
http://tgdtheory.fi/public_html/bioware/bioware.html#tubuc, 2006.
[K9] M. Pitkanen. Quantum Astrophysics. In Physics in Many-Sheeted Space-Time. Onlinebook.
http://tgdtheory.fi/public_html/tgdclass/tgdclass.html#qastro, 2006.
[K10] M. Pitkanen. Quantum Model for Nerve Pulse. In TGD and EEG. Onlinebook. http://
tgdtheory.fi/public_html//tgdeeg/tgdeeg/tgdeeg.html#pulse, 2006.
[K11] M. Pitkanen. TGD and Astrophysics. In Physics in Many-Sheeted Space-Time. Onlinebook.
http://tgdtheory.fi/public_html/tgdclass/tgdclass.html#astro, 2006.
[K12] M. Pitkanen. Three new physics realizations of the genetic code and the role of dark matter
in bio-systems. In Genes and Memes. Onlinebook. http://tgdtheory.fi/public_html/
genememe/genememe.html#dnatqccodes, 2006.
[K13] M. Pitkanen. Topological Quantum Computation in TGD Universe. In Genes and Memes.
Onlinebook. http://tgdtheory.fi/public_html/genememe/genememe.html#tqc, 2006.
Downloads
Published
Issue
Section
License
Authors who publish with this journal agree to the following terms:- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).